STAT5 Transcription Factor

A signal transducer and activator of transcription that mediates cellular responses to a variety of CYTOKINES. Stat5 activation is associated with transcription of CELL CYCLE regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many patients with acute MYELOID LEUKEMIA.

Also Known As:

Mammary Gland Factor; Mammary Gland-Specific Nuclear Factor; STAT5 Protein; STAT5a Protein; STAT5a Transcription Factor; STAT5alpha Protein; STAT5b Protein; STAT5b Transcription Factor; STAT5beta Protein; Signal Transducer and Activator of Transcription 5; Signal Transducer and Activator of Transcription 5A; Signal Transducer and Activator of Transcription 5B; Factor, STAT5 Transcription; Mammary Gland Specific Nuclear Factor; Transcription Factor, STAT5; Transcription Factor, STAT5a; Transcription Factor, STAT5b

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Transcription Factors: 39842
    - STAT Transcription Factors: 46
      - STAT5 Transcription Factor: 231
  - Carrier Proteins: 13306
    - Signal Transducing Adaptor Proteins
      - STAT Transcription Factors: 46
        STAT5 Transcription Factor: 231
  - Intracellular Signaling Peptides and Proteins: 32
    - Signal Transducing Adaptor Proteins
      - STAT Transcription Factors: 46
        STAT5 Transcription Factor: 231
- Peptides: 84029
  - Intracellular Signaling Peptides and Proteins: 32
    - Signal Transducing Adaptor Proteins
      - STAT Transcription Factors: 46
        STAT5 Transcription Factor: 231

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Ichio Imamura Research Topics

Disease

Drug/Important Bio-Agent (IBA)